Autoimmune disorder is a clinical syndrome in which a decreased number of circulating platelets (thrombocytopenia) manifests as a bleeding tendency, easy bruising (purpura), or extravasation of blood from capillaries into skin and mucous membranes (petechiae). Although most cases of acute ITP, particularly in children, are mild and self-limited, intracranial hemorrhage may occur when the platelet count drops below 10 x 109/L (< 10 x 103/μL); this occurs in 0.5-1% of children, and half of these cases are fatal.
ALLOGENEIC STEM CELL TRANSPLANT
A stem cell transplant â€” also called a blood or marrow transplant â€” is the injection or infusion of healthy stem cells into your body to replace damaged or diseased stem cells. A stem cell transplant may be necessary if your bone marrow stops working and doesn’t produce enough healthy stem cells.